Benefits of Ashwagandha Root


Ashwagandha (Withania somnifera) is an herb from the Indian Himalayas. In Ayurvedic Medicine - it is used as an Rasayana (tonic) supporting:

  • Immunity
  • Mental Focus
  • Resistance to Stress 
  • Muscle Synthesis & Recovery

This month, search terms Ashwagandha Benefits increased by a staggering 700% - with a steady climb. 

    In this blog we discuss all things Ashwagandha -  its relationship to clinical success, and as a treatment modality for common health concerns. 

    Always consult a health care professional before consuming Ashwagandha. This blog is for information purposes only and is not for the diagnosis, treatment, or management of disease.  


    How does Ashwagandha Work

    Ashwagandha has been associated with modulating:

    • Brain
    • Thyroid
    • Immune cells
    • Muscle metabolism

    & Mental (cognitive) features such as anxiety, attention, and focus


    The Chemistry of Ashwagandha

    The chemicals in Ashwagandha have been shown to exert beneficial effects on humans - specifically, the Withania species, a form of phytonutrients filled with Alkaloids, Flavonoids, and Tannins. 

    All of which known for there Immune, Brain, Antioxidant capacity.

      However, the traditional Indian system of medicine called “Ayurveda” recommends using Withania somnifera roots for therapeutic purposes and internal administration.

      The chemical constituents of roots include

      • Withaferin A
      • Withanosides
      • Withanolide A
      • Withanolide B

      Shop KSM-66 Extracts: Ashwagandha KSM-66 Withanolide Extract

       kipos nutrimart ashwagandha what is it and benefits google blog picture visual description and explanation ashwagandha for stress mood anxiety mental health and weight training

      Benefits of Ashwagandha

      Ashwagandha & Cognition

      Ashwagandha has been associated with improving Cognition.

      The part of the brain that deals with Executive Functioning, often described as the set of mental skills that include:

      • Working Memory
      • Flexible Thinking
      • Focus and Attention
      • Self & Impulse Control


      Research Evidence

      In a double-blind study, Ashwagandha Rt Extract (ARE)(KSM-66) was studied to determine its ability to improve cognitive function, specifically memory – in adults that showed specific signs of aging.

      Groups were treated with either KSM-66 (300mg), or placebo twice daily for a total of eight weeks. Subtest scores were recorded for logical memory, verbal memory, faces, and family pictures.

      In the Ashwagandha group, improvements were noted in immediate recall, and general memory – specifically logical memory (in psychology, local memory refers to the memory for the meaning of learned material)

      The Ashwagandha group also demonstrated significantly improvement in:

      • Executive Function
      • Sustained Attention
      • Information-Processing Speed

      These tests are used commonly in psychology research practices and reflect effects on the ability to think (cognitive function).


      Ashwagandha & Stress

      Stress is a term with many definitions, in the event of of this blog, stress can be considered: 

      A negative appraisal towards an event, offsetting a potential cluster of physical and or mental responses. 

      Physical symptoms of stress:

      • Chest Pain
      • Heightened blood pressure
      • Increased heart and breathing rate
      • Muscular Tension & Jaw Clenching

      Mental symptoms of stress: 

      • Fatigue & Brain Fog
      • Anxiety & Depression
      • Anger & Irritability & Restlessness
      • Difficulty with Memory and Concentration

      Ashwagandha Root Supplement what is ashwagandha what are the benefits to ashwagandha

      Tea & Beverages 

      Ashwagandha & Stress

      The stress-hormone cortisol is an important factor in the stress-response.

      Cortisol is influenced by a deep structure in the brain called the 

      • Hypothalamic Pituitary Axis (HPA axis).

      Prolonged release of cortisol caused by chronic stress can contribute to the general decline of health, affecting:

      • Mood
      • Kidneys
      • Attention & Focus
      • Heart and Blood Vessels

      In a 2019 research article, consuming Ashwagandha after 12 weeks was associated with 30% decrease in listed anxiety symptoms. These symptoms were scaled via the Hamilton Anxiety Rating Scale (HAM-A), and self-report Depression, Anxiety, Stress Scale-21 (DASS-21). (Two self-report scales used by clinical psychologist and researchers)

      Ashwagandha intake was also associated with greater reductions in morning cortisol (P < .001). The benefits of Ashwagandha have been associated with moderating effect on the hypothalamus-pituitary-adrenal axis.


      Stress & Health Decline

      In 1946, a scientist Hans Selye noticed that many people experiencing chronic stress generally declined in their health much sooner than self-reported healthy individuals.

      His research on the topic lead him to theorizing General Adaptation Syndrome (GAS) and how long-term stress (caused by prolonged Autonomic Response prompt by cortisol) perpetuated the cycle of declining health.

      The symptoms of decline were often related to the many physical and emotion faucets that contribute to overall health & longevity.   

      • Mental Agility
      • Kidney & Nervous Function
      • Chronic organ diseases like heart disease

      Proper consumption of nutrients that support the replenishment of stress organs are essential, 

      Today this nutrient is commonly known as adaptogens.

      Ashwagandha is considered an Adaptogen dating back to traditional Indian Medicine, considered a Rasayana (Rejuvenating Tonic)


      Ashwagandha & Immunity

      One of the main actives in Ashwagandha are called Withanolides, mainly withanolide glycosides.

      It has been suggested that this compound provides immune-benefits by activating white blood cells like macrophages. Macrophages function by eliminating invading bacteria.

      Ashwagandha roots and leaves have been show to activate lysosomal enzymes which function to detoxify and eliminate by-products of immune cells.

      In one study, Ashwagandha consumption increased expression levels of T-helper 1 (Th1) cytokines, and enhanced natural killer (NK) cell activity.

      To date, many studies of Ashwagandha suggest it has the ability to impact multiple layers of immune function:

      Innate Immunity 

      • Immunity Present in the Body
      • Non-Specific Immunity ready to Invade
      • First-Response Immunity to foreign Pathogens
      • No Memory to this Immune system

      Adaptive immunity

      • Created in response to foreign subject
      • Specific Immunity to Specific Infection
      • Onset Response: 1 to 2 weeks
      • Memory of Specific Foreign Invaders  

      It is clear that Ashwagandha interacts with our systems that help replenish us from the constant exposure and carcinogens caused by everyday pollution, and mother nature.

      Ashwagandha Probiotics


      Ashwagandha, Immunity & Stress Hormone Cortisol

      In many ways Ashwagandha, and how it exerts its beneficial effects is still widely a mystery. Some researchers suggest its ability to modulate the stress hormone cortisol, may contribute to its immunity benefits.

      It is widely known that unbalanced cortisol levels caused by our natural response system, primary disease or long-term stress, can increase the likelihood of being immunocompromised.

      How Could Stress “Get inside the body” to affect the Immune response?

      It was been shown that chronic forms of stress were accompanied by reduced natural killer cell

      • Cytotoxicity
      • Suppressed lymphocyte proliferative responses
      • Blunted humoral responses to immunization


      Immunity, Mood, Cortisol

      The long-term immune state perpetuated by cortisol has been correlated to called sickness behavior, a syndrome that involved a cluster of changes such as:

      Reduction in:

      • Physical Activity
      • Social interaction
      • Sexual activity

      Increased responsiveness to:

      • Pain
      • Anorexia
      • Depressed mood

      Consuming a variety of adaptogens that influence cortisol response is an effective way of nutritional lifestyle management that can promote rebalance and rejuvenation in a fatigued system.

      Listed are our top ranked Adaptogens:

      Ashwagandha and Testosterone for weight training and resistance training, muscle gain and ashwagandha and testosterone what is ashwagandha

      Ashwagandha & Resistance Training 

      The link between Ashwagandha and Testosterone has been a topic of interest for several years, 

      In an 8-week, randomized, double-blind, placebo, controlled clinical study, 57 young male subjects (18-50 years old) were divided into two groups.

      Men in the treatment group consumed 300mg of Ashwagandha Root Extract twice daily (t=300mg, twice daily = 300mg).

      Following initial measurements, both groups participated in an 8-week resistance training program.

      At the end of the trial, the ashwagandha treatment group had significantly greater increase in muscle strength, recorded via bench-press exercises, and leg extensions.

      The treatment group also recorded a significantly greater muscle size increase in the biceps and chest, a greater reduction of exercise-induced muscle damage, a significant increase in testosterone, and significantly greater decrease in body fat percentage compared to the placebo subjects.

      Although the exact mechanism of Ashwagandha is unknown, some authors suggest ashwagandha

      • Can have beneficial effects on mitochondrial energy levels and functioning and reduce the activity of the Mg2 + -dependent ATPase enzyme responsible for the breakdown of ATP.
      • Can increase creatine levels that can in turn lead to ATP generation
      • Finally, the effects of ashwagandha on the nervous system as anti-anxiety agent and in promoting focus and concentration


      How can Ashwagandha be Consumed

      Standardized Extracts 

      Organic Powders for Smoothies


      Tea & Beverages 







      Leave a comment

      All comments are moderated before being published